Reaction Details Report a problem with these data
Target
Soluble acetylcholine receptor
Ligand
BDBM50190786
Substrate
n/a
Meas. Tech.
Creating an a7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein
pH
7.4±n/a
Temperature
293.15±n/a K
Ki
15000±n/a nM
Citation
 Nemecz, Akos; Taylor, Palmer  Creating an a7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein Taylor Research Group 0:0 (2014)   
Target
Name:
Soluble acetylcholine receptor
Synonyms:
Acetylcholine Binding protein | Soluble acetylcholine receptor
Type:
n/a
Mol. Mass.:
26560.08
Organism:
Aplysia Californica
Description:
Q8WSF8
Residue:
236
Sequence:
MLVSVYLALLVACVGQAHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRAGNGFFRNLFD
  
Inhibitor
Name:
BDBM50190786
Synonyms:
(R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxamide | CHEMBL214268 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide | PHA-543613 | PHA543613
Type:
Small organic molecule
Emp. Form.:
C15H17N3O2
Mol. Mass.:
271.3144
SMILES:
O=C(N[C@H]1CN2CCC1CC2)c1cc2ccoc2cn1 |wU:3.2,(-5.16,-23.46,;-5.16,-25,;-3.82,-25.76,;-2.49,-24.99,;-2.5,-23.45,;-1.16,-22.68,;.18,-23.45,;.18,-24.99,;-1.15,-25.76,;-2.03,-24.61,;-1.21,-23.81,;-6.49,-25.78,;-7.83,-25.01,;-9.15,-25.79,;-10.62,-25.31,;-11.52,-26.55,;-10.62,-27.8,;-9.16,-27.33,;-7.82,-28.1,;-6.48,-27.33,)|
Structure:
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