Reaction Details Report a problem with these data
Target
Protein RecA
Ligand
BDBM92394
Substrate
n/a
Meas. Tech.
Fluorescent Reporter Assay
IC50
>2.00e+5±n/a nM
Citation
 Zhang, L; Zheng, Y; Callahan, B; Belfort, M; Liu, Y Cisplatin inhibits protein splicing, suggesting inteins as therapeutic targets in mycobacteria. J Biol Chem 286:1277-82 (2011) [PubMed]  Article 
Target
Name:
Protein RecA
Synonyms:
RECA_ECOLI | lexB | recA | recH | rnmB | tif | umuB | zab
Type:
Protein
Mol. Mass.:
37964.88
Organism:
Escherichia coli
Description:
C6EJT2
Residue:
353
Sequence:
MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
  
Inhibitor
Name:
BDBM92394
Synonyms:
trans-EE, 9
Type:
Small organic molecule
Emp. Form.:
C6H16Cl2N2O2Pt
Mol. Mass.:
414.193
SMILES:
COC(C)N[Pt](Cl)(Cl)NC(C)OC
Structure:
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