Reaction Details Report a problem with these data
Target
Pyrazinamidase/nicotinamidase PncA
Ligand
BDBM50026863
Substrate
n/a
Meas. Tech.
Enzyme Assay
Ki
3e+2± 1e+2 nM
Citation
 Seiner, DR; Hegde, SS; Blanchard, JS Kinetics and inhibition of nicotinamidase from Mycobacterium tuberculosis. Biochemistry 49:9613-9 (2010) [PubMed]  Article 
Target
Name:
Pyrazinamidase/nicotinamidase PncA
Synonyms:
Nicotinamidase (PncA) | Pyrazinamidase
Type:
Enzyme
Mol. Mass.:
19590.80
Organism:
Mycobacterium tuberculosis
Description:
Q50575
Residue:
186
Sequence:
MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGADFHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLTAGVSADTTVAALEEMRTASVELVCSS
  
Inhibitor
Name:
BDBM50026863
Synonyms:
CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA Inhibitor, 2 | Pyridine-3-carbaldehyde
Type:
Small organic molecule
Emp. Form.:
C6H5NO
Mol. Mass.:
107.11
SMILES:
O=Cc1cccnc1
Structure:
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