Reaction Details Report a problem with these data
Target
Pyrazinamidase/nicotinamidase PncA
Ligand
BDBM92860
Substrate
n/a
Meas. Tech.
Enzyme Assay
Ki
6.3e+4± 3.1e+4 nM
Citation
 Seiner, DR; Hegde, SS; Blanchard, JS Kinetics and inhibition of nicotinamidase from Mycobacterium tuberculosis. Biochemistry 49:9613-9 (2010) [PubMed]  Article 
Target
Name:
Pyrazinamidase/nicotinamidase PncA
Synonyms:
Nicotinamidase (PncA) | Pyrazinamidase
Type:
Enzyme
Mol. Mass.:
19590.80
Organism:
Mycobacterium tuberculosis
Description:
Q50575
Residue:
186
Sequence:
MRALIIVDVQNDFCEGGSLAVTGGAALARAISDYLAEAADYHHVVATKDFHIDPGDHFSGTPDYSSSWPPHCVSGTPGADFHPSLDTSAIEAVFYKGAYTGAYSGFEGVDENGTPLLNWLRQRGVDEVDVVGIATDHCVRQTAEDAVRNGLATRVLVDLTAGVSADTTVAALEEMRTASVELVCSS
  
Inhibitor
Name:
BDBM92860
Synonyms:
PncA Inhibitor, 4
Type:
Small molecule
Emp. Form.:
C6H7NO
Mol. Mass.:
109.1259
SMILES:
OCc1cccnc1
Structure:
Search PDB for entries with ligand similarity: