Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM67266
Substrate
n/a
IC50
>49735±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM67266
Synonyms:
4-chloranyl-1-ethyl-3-nitro-quinolin-2-one | 4-chloro-1-ethyl-3-nitro-2-quinolinone | 4-chloro-1-ethyl-3-nitro-carbostyril | 4-chloro-1-ethyl-3-nitroquinolin-2-one | MLS000718723 | SMR000290991 | cid_800048
Type:
Small organic molecule
Emp. Form.:
C11H9ClN2O3
Mol. Mass.:
252.654
SMILES:
CCn1c2ccccc2c(Cl)c([N+]([O-])=O)c1=O
Structure:
Search PDB for entries with ligand similarity: