Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM63629
Substrate
n/a
IC50
>49746±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM63629
Synonyms:
4,5-bis(bromanyl)-2-(4-methylphenyl)pyridazin-3-one | 4,5-dibromo-2-(4-methylphenyl)-3(2H)-pyridazinone | 4,5-dibromo-2-(4-methylphenyl)-3-pyridazinone | 4,5-dibromo-2-(4-methylphenyl)pyridazin-3-one | 4,5-dibromo-2-(p-tolyl)pyridazin-3-one | MLS000720992 | SMR000335544 | cid_1487485
Type:
Small organic molecule
Emp. Form.:
C11H8Br2N2O
Mol. Mass.:
344.002
SMILES:
Cc1ccc(cc1)-n1ncc(Br)c(Br)c1=O
Structure:
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