Reaction Details
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Protein skinhead-1
Ligand
BDBM47960
Substrate
n/a
IC50
20600±n/a nM
Citation
PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
Inhibitor
Name:
BDBM47960
Synonyms:
MLS000732969 | N-[(2-biphenyl-4-yl-5-methyl-1,3-oxazol-4-yl)methyl]-N-methyltetrahydrofuran-3-amine | N-methyl-N-[[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]methyl]oxolan-3-amine | N-methyl-N-[[5-methyl-2-(4-phenylphenyl)-4-oxazolyl]methyl]-3-oxolanamine | SMR000316222 | cid_16191300 | methyl-[[5-methyl-2-(4-phenylphenyl)oxazol-4-yl]methyl]-tetrahydrofuran-3-yl-amine
Type:
Small organic molecule
Emp. Form.:
C22H24N2O2
Mol. Mass.:
348.4382
SMILES:
CN(Cc1nc(oc1C)-c1ccc(cc1)-c1ccccc1)C1CCOC1
Structure:
