Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93802
Substrate
n/a
IC50
47700±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93802
Synonyms:
MLS000680722 | N-[4-(2,4-difluorophenyl)-2-thiazolyl]carbamic acid ethyl ester | N-[4-(2,4-difluorophenyl)thiazol-2-yl]carbamic acid ethyl ester | SMR000272449 | cid_887761 | ethyl N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]carbamate | ethyl N-[4-[2,4-bis(fluoranyl)phenyl]-1,3-thiazol-2-yl]carbamate | ethyl [4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]carbamate
Type:
Small organic molecule
Emp. Form.:
C12H10F2N2O2S
Mol. Mass.:
284.282
SMILES:
CCOC(=O)Nc1nc(cs1)-c1ccc(F)cc1F
Structure:
Search PDB for entries with ligand similarity: