Reaction Details Report a problem with these data
Target
Perilipin-1
Ligand
BDBM94500
Substrate
n/a
IC50
6301±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-1
Synonyms:
PERI | PLIN | PLIN1 | PLIN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55988.69
Organism:
Homo sapiens (Human)
Description:
gi_223718203
Residue:
522
Sequence:
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
  
Inhibitor
Name:
BDBM94500
Synonyms:
(E)-2-butenedioic acid;1-[2-(dimethylamino)ethylamino]-2-methoxy-4-methyl-9-thioxanthenone | (E)-but-2-enedioic acid;1-[2-(dimethylamino)ethylamino]-2-methoxy-4-methyl-thioxanthen-9-one | (E)-but-2-enedioic acid;1-[2-(dimethylamino)ethylamino]-2-methoxy-4-methylthioxanthen-9-one | 1-[2-(dimethylamino)ethylamino]-2-methoxy-4-methyl-thioxanthen-9-one;fumaric acid | MLS003116011 | SMR001831569 | cid_5384288
Type:
Small organic molecule
Emp. Form.:
C19H22N2O2S
Mol. Mass.:
342.455
SMILES:
COc1cc(C)c2sc3ccccc3c(=O)c2c1NCCN(C)C
Structure:
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