Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM82958
Substrate
n/a
IC50
10900±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM82958
Synonyms:
4-[[2-(4-nitrophenyl)-4-quinazolinyl]amino]benzoic acid | 4-[[2-(4-nitrophenyl)quinazolin-4-yl]amino]benzoic acid | 4-{[2-(4-nitrophenyl)quinazolin-4-yl]amino}benzoic acid | MLS001196815 | SMR000555964 | cid_1187249
Type:
Small organic molecule
Emp. Form.:
C21H14N4O4
Mol. Mass.:
386.3603
SMILES:
OC(=O)c1ccc(Nc2nc(nc3ccccc23)-c2ccc(cc2)[N+]([O-])=O)cc1
Structure:
Search PDB for entries with ligand similarity: