Reaction Details
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Report a problem with these dataTarget
Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM76075
Substrate
n/a
IC50
21600±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM76075
Synonyms:
2-(2,4-dimethylphenyl)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]quinoline-4-carboxamide | 2-(2,4-dimethylphenyl)-N-[4-(2-thiazolylsulfamoyl)phenyl]-4-quinolinecarboxamide | 2-(2,4-dimethylphenyl)-N-[4-(thiazol-2-ylsulfamoyl)phenyl]cinchoninamide | MLS-0203836.0001 | cid_1358622
Type:
Small organic molecule
Emp. Form.:
C27H22N4O3S2
Mol. Mass.:
514.619
SMILES:
Cc1ccc(c(C)c1)-c1cc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nccs2)c2ccccc2n1
Structure:
