Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95345
Substrate
n/a
IC50
>155028±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM95345
Synonyms:
(E)-2-cyano-3-(2-methoxyanilino)-2-propenoic acid ethyl ester | (E)-2-cyano-3-(o-anisidino)acrylic acid ethyl ester | 2-Cyano-3-(2-methoxy-phenylamino)-acrylic acid ethyl ester | MLS000568396 | SMR000176454 | cid_3125195 | ethyl (E)-2-cyano-3-(2-methoxyanilino)prop-2-enoate | ethyl (E)-2-cyano-3-[(2-methoxyphenyl)amino]prop-2-enoate
Type:
Small organic molecule
Emp. Form.:
C13H14N2O3
Mol. Mass.:
246.2619
SMILES:
CCOC(=O)C(C=Nc1ccccc1OC)C#N |w:7.7|
Structure:
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