Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 5 group A member 2
Ligand
BDBM95487
Substrate
n/a
IC50
>35863±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 5 group A member 2
Synonyms:
Alpha-1-fetoprotein transcription factor | B1-binding factor | B1F | CPF | CYP7A promoter-binding factor | FTF | Hepatocytic transcription factor | LRH-1 | Liver Receptor Homolog 1 | NR5A2 | NR5A2_HUMAN | Nuclear receptor subfamily 5 group A member 2 | hB1F | nuclear receptor subfamily 5 group A member 2 isoform 2
Type:
Nuclear Hormone Receptor
Mol. Mass.:
61341.37
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
  
Inhibitor
Name:
BDBM95487
Synonyms:
MLS000566229 | N-[2-(1-cyclohexenyl)ethyl]-2-[4-(3,4-dimethoxyphenyl)-4-methyl-2,5-dioxo-1-imidazolidinyl]acetamide | N-[2-(cyclohexen-1-yl)ethyl]-2-[4-(3,4-dimethoxyphenyl)-2,5-diketo-4-methyl-imidazolidin-1-yl]acetamide | N-[2-(cyclohexen-1-yl)ethyl]-2-[4-(3,4-dimethoxyphenyl)-4-methyl-2,5-bis(oxidanylidene)imidazolidin-1-yl]ethanamide | N-[2-(cyclohexen-1-yl)ethyl]-2-[4-(3,4-dimethoxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide | SMR000153386 | cid_9551986
Type:
Small organic molecule
Emp. Form.:
C22H29N3O5
Mol. Mass.:
415.4828
SMILES:
COc1ccc(cc1OC)C1(C)NC(=O)N(CC(=O)NCCC2=CCCCC2)C1=O |t:23|
Structure:
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