Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM82656
Substrate
n/a
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM82656
Synonyms:
4-bromobenzaldehyde (5-chloro-6-oxo-1-phenyl-1,6-dihydro-4-pyridazinyl)hydrazone | 5-[(N''E)-N''-(4-bromobenzylidene)hydrazino]-4-chloro-2-phenyl-pyridazin-3-one | 5-[(N'E)-N'-(4-bromobenzylidene)hydrazino]-4-chloro-2-phenyl-pyridazin-3-one | 5-[2-[(4-bromophenyl)methylidene]hydrazinyl]-4-chloranyl-2-phenyl-pyridazin-3-one | 5-[2-[(4-bromophenyl)methylidene]hydrazinyl]-4-chloro-2-phenyl-3-pyridazinone | 5-[2-[(4-bromophenyl)methylidene]hydrazinyl]-4-chloro-2-phenylpyridazin-3-one | 5-[N'-(4-bromobenzylidene)hydrazino]-4-chloro-2-phenyl-pyridazin-3-one | MLS000545718 | SMR000162973 | cid_2787935
Type:
Small organic molecule
Emp. Form.:
C17H12BrClN4O
Mol. Mass.:
403.66
SMILES:
Clc1c(cnn(-c2ccccc2)c1=O)N=NCc1ccc(Br)cc1 |w:14.15|
Structure:
Search PDB for entries with ligand similarity: