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Target
Fructose-bisphosphate aldolase
Ligand
BDBM96172
Substrate
n/a
IC50
>370.01±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis PubChem Bioassay (2013)[AID] 
Target
Name:
Fructose-bisphosphate aldolase
Synonyms:
ALF_MYCTU | FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-1,6-bisphosphate aldolase (FBA) | Fructose-bisphosphate aldolase | Probable fructose-bisphosphate aldolase Fba | fba
Type:
Protein
Mol. Mass.:
36539.01
Organism:
Mycobacterium tuberculosis (strain H37Rv)
Description:
P9WQA3
Residue:
344
Sequence:
MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
  
Inhibitor
Name:
BDBM96172
Synonyms:
3-(5-methyl-2-furanyl)-2,5-diphenyl-3,4-dihydropyrazole | 3-(5-methylfuran-2-yl)-2,5-diphenyl-3,4-dihydropyrazole | 5-(5-methyl-2-furyl)-1,3-diphenyl-2-pyrazoline | 5-(5-methyl-2-furyl)-1,3-diphenyl-4,5-dihydro-1H-pyrazole | MLS000702375 | SMR000225051 | cid_560996
Type:
Small organic molecule
Emp. Form.:
C20H18N2O
Mol. Mass.:
302.3697
SMILES:
Cc1ccc(o1)C1CC(=NN1c1ccccc1)c1ccccc1 |c:9|
Structure:
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