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Target
Fructose-bisphosphate aldolase
Ligand
BDBM96224
Substrate
n/a
IC50
894.94±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis PubChem Bioassay (2013)[AID] 
Target
Name:
Fructose-bisphosphate aldolase
Synonyms:
ALF_MYCTU | FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-1,6-bisphosphate aldolase (FBA) | Fructose-bisphosphate aldolase | Probable fructose-bisphosphate aldolase Fba | fba
Type:
Protein
Mol. Mass.:
36539.01
Organism:
Mycobacterium tuberculosis (strain H37Rv)
Description:
P9WQA3
Residue:
344
Sequence:
MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
  
Inhibitor
Name:
BDBM96224
Synonyms:
2-(3,4-Dimethyl-phenyl)-2H-benzotriazol-5-ylamine | 2-(3,4-dimethylphenyl)-5-benzotriazolamine | 2-(3,4-dimethylphenyl)benzotriazol-5-amine | MLS001209723 | SMR000515206 | [2-(3,4-dimethylphenyl)benzotriazol-5-yl]amine | cid_835193
Type:
Small organic molecule
Emp. Form.:
C14H14N4
Mol. Mass.:
238.2878
SMILES:
Cc1ccc(cc1C)-n1nc2ccc(N)cc2n1
Structure:
Search PDB for entries with ligand similarity: