Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM96299
Substrate
n/a
IC50
>118613±n/a nM
Citation
 PubChem, PC Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2013)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM96299
Synonyms:
(3,5-dimethylphenyl)-(5-naphthalen-2-yl-1H-imidazol-2-yl)methanol | (3,5-dimethylphenyl)-[5-(2-naphthalenyl)-1H-imidazol-2-yl]methanol | (3,5-dimethylphenyl)-[5-(2-naphthyl)-1H-imidazol-2-yl]methanol | MLS003123567 | SMR001291538 | cid_49790119
Type:
Small organic molecule
Emp. Form.:
C22H20N2O
Mol. Mass.:
328.407
SMILES:
Cc1cc(C)cc(c1)C(O)c1nc(c[nH]1)-c1ccc2ccccc2c1
Structure:
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