Reaction Details
Report a problem with these data
Report a problem with these dataTarget
T cell receptor alpha variable 4
Ligand
BDBM96325
Substrate
n/a
IC50
17617±n/a nM
Citation
PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
Inhibitor
Name:
BDBM96325
Synonyms:
MLS000401502 | N-(3-morpholin-4-ylsulfonylphenyl)-4-[(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)sulfonyl]benzamide | N-(3-morpholinosulfonylphenyl)-4-[(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)sulfonyl]benzamide | N-[3-(4-morpholinylsulfonyl)phenyl]-4-[(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)sulfonyl]benzamide | SMR000243199 | cid_4295603
Type:
Small organic molecule
Emp. Form.:
C27H35N3O6S2
Mol. Mass.:
561.713
SMILES:
[H]C12CC(C)(CN1S(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(c1)S(=O)(=O)N1CCOCC1)CC(C)(C)C2 |TLB:7:6:2:35.34.38|
Structure:
