Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM96328
Substrate
n/a
IC50
49103±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM96328
Synonyms:
3-[methyl(phenyl)sulfamoyl]benzoic acid [2-(3-acetylanilino)-2-keto-1-phenyl-ethyl] ester | 3-[methyl(phenyl)sulfamoyl]benzoic acid [2-(3-acetylanilino)-2-oxo-1-phenylethyl] ester | MLS000394843 | SMR000242905 | [2-(3-acetylanilino)-2-oxo-1-phenylethyl] 3-[methyl(phenyl)sulfamoyl]benzoate | [2-[(3-ethanoylphenyl)amino]-2-oxidanylidene-1-phenyl-ethyl] 3-[methyl(phenyl)sulfamoyl]benzoate | cid_4638263
Type:
Small organic molecule
Emp. Form.:
C30H26N2O6S
Mol. Mass.:
542.602
SMILES:
CN(c1ccccc1)S(=O)(=O)c1cccc(c1)C(=O)OC(C(=O)Nc1cccc(c1)C(C)=O)c1ccccc1
Structure:
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