Reaction Details
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Report a problem with these dataTarget
T cell receptor alpha variable 4
Ligand
BDBM96345
Substrate
n/a
IC50
24600±n/a nM
Citation
PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
Inhibitor
Name:
BDBM96345
Synonyms:
2-hydroxy-3,5,7-trimethylol-cyclohepta-2,4,6-trien-1-one | 2-hydroxy-3,5,7-tris(hydroxymethyl)-1-cyclohepta-2,4,6-trienone | 2-hydroxy-3,5,7-tris(hydroxymethyl)cyclohepta-2,4,6-trien-1-one | 3,5,7-tris(hydroxymethyl)-2-oxidanyl-cyclohepta-2,4,6-trien-1-one | MLS000766751 | SMR000339647 | cid_741311
Type:
Small organic molecule
Emp. Form.:
C10H12O5
Mol. Mass.:
212.1993
SMILES:
OCc1cc(CO)c(O)c(=O)c(CO)c1
Structure:
