Reaction Details
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Report a problem with these dataTarget
T cell receptor alpha variable 4
Ligand
BDBM51295
Substrate
n/a
IC50
3736±n/a nM
Citation
PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
Inhibitor
Name:
BDBM51295
Synonyms:
8-Amino-2-thioxo-2,3-dihydro-1H-benzo[g]pteridin-4-one | 8-amino-2-sulfanylidene-1H-benzo[g]pteridin-4-one | 8-amino-2-thioxo-1H-benzo[g]pteridin-4-one | 8-azanyl-2-sulfanylidene-1H-benzo[g]pteridin-4-one | MLS000776691 | SMR000413090 | cid_5417965
Type:
Small organic molecule
Emp. Form.:
C10H7N5OS
Mol. Mass.:
245.26
SMILES:
Nc1ccc2nc3c(nc2c1)[nH]c(=S)[nH]c3=O
Structure:
