Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM96367
Substrate
n/a
IC50
>94024±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM96367
Synonyms:
3,4,5-trihydroxy-N'-[(1E)-pyridin-3-ylmethylene]benzohydrazide | 3,4,5-trihydroxy-N-[(E)-3-pyridinylmethylideneamino]benzamide | 3,4,5-trihydroxy-N-[(E)-3-pyridylmethyleneamino]benzamide | 3,4,5-trihydroxy-N-[(E)-pyridin-3-ylmethylideneamino]benzamide | 3,4,5-tris(oxidanyl)-N-[(E)-pyridin-3-ylmethylideneamino]benzamide | MLS001194589 | SMR000554979 | cid_9615897
Type:
Small organic molecule
Emp. Form.:
C13H11N3O4
Mol. Mass.:
273.2441
SMILES:
Oc1cc(cc(O)c1O)C(=O)N\N=C\c1cccnc1
Structure:
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