Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM61896
Substrate
n/a
IC50
6250±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM61896
Synonyms:
2-(3,4-dihydroxyphenyl)-4-benzo[h][1]benzopyranone | 2-(3,4-dihydroxyphenyl)benzo[h]chromen-4-one | 2-[3,4-bis(oxidanyl)phenyl]benzo[h]chromen-4-one | 3',4'-DIHYDROXY-a-NAPHTHOFLAVONE | MLS001360569 | SMR001223866 | cid_676291
Type:
Small organic molecule
Emp. Form.:
C19H12O4
Mol. Mass.:
304.2962
SMILES:
Oc1ccc(cc1O)-c1cc(=O)c2ccc3ccccc3c2o1
Structure:
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