Reaction Details
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Report a problem with these dataTarget
T cell receptor alpha variable 4
Ligand
BDBM41891
Substrate
n/a
IC50
>94047±n/a nM
Citation
PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
Inhibitor
Name:
BDBM41891
Synonyms:
1-(3,4-dihydroxyphenyl)-2-(2-methyl-1-benzimidazolyl)ethanone;hydrochloride | 1-(3,4-dihydroxyphenyl)-2-(2-methylbenzimidazol-1-yl)ethanone;hydrochloride | 1-[3,4-bis(oxidanyl)phenyl]-2-(2-methylbenzimidazol-1-yl)ethanone;hydrochloride | CHEMBL597055 | MLS-0315854.0001 | cid_25067495
Type:
Small organic molecule
Emp. Form.:
C16H14N2O3
Mol. Mass.:
282.294
SMILES:
Cc1nc2ccccc2n1CC(=O)c1ccc(O)c(O)c1
Structure:
