Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96586
Substrate
n/a
EC50
>29910±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G protein alpha 16 | G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | Guanine nucleotide-binding protein subunit alpha-15 [Y147C]
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96586
Synonyms:
2-[2-(cyclohexen-1-yl)ethylcarbamoyl]bicyclo[2.2.1]hept-5-ene-3-carboxylic acid | 2-[[2-(1-cyclohexenyl)ethylamino]-oxomethyl]-3-bicyclo[2.2.1]hept-5-enecarboxylic acid | MLS000107969 | SMR000103933 | cid_2862533
Type:
Small organic molecule
Emp. Form.:
C17H23NO3
Mol. Mass.:
289.3694
SMILES:
[H]C12CC([H])(C=C1)C(C2C(O)=O)C(=O)NCCC1=CCCCC1 |c:5,t:19,TLB:9:8:2:5.6,THB:12:7:2:5.6|
Structure:
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