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Target
Kallikrein-7
Ligand
BDBM100096
Substrate
n/a
EC50
>69555±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100096
Synonyms:
2,7-Dimethyl-imidazo[1,2-a]pyridine-3-carboxylic acid (2,5-dimethoxy-benzylidene)-hydrazide | MLS001207467 | N-[(Z)-(2,5-dimethoxybenzylidene)amino]-2,7-dimethyl-imidazo[1,2-a]pyridine-3-carboxamide | N-[(Z)-(2,5-dimethoxyphenyl)methylideneamino]-2,7-dimethyl-3-imidazo[1,2-a]pyridinecarboxamide | N-[(Z)-(2,5-dimethoxyphenyl)methylideneamino]-2,7-dimethyl-imidazo[1,2-a]pyridine-3-carboxamide | N-[(Z)-(2,5-dimethoxyphenyl)methylideneamino]-2,7-dimethylimidazo[1,2-a]pyridine-3-carboxamide | SMR000514502 | cid_5340453
Type:
Small organic molecule
Emp. Form.:
C19H20N4O3
Mol. Mass.:
352.3871
SMILES:
COc1ccc(OC)c(\C=N/NC(=O)c2c(C)nc3cc(C)ccn23)c1
Structure:
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