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Target
Melatonin receptor type 1A
Ligand
BDBM103456
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
0.095±0.0 nM
Citation
 Uchikawa, O; Koike, T; Hoashi, Y; Takai, T Tricyclic compound and pharmaceutical use thereof US Patent  US8552037 Publication Date 10/8/2013 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM103456
Synonyms:
US8552037, 123
Type:
Small organic molecule
Emp. Form.:
C15H15F3N2O2
Mol. Mass.:
312.287
SMILES:
Cc1nc2ccc3CCC(CCNC(=O)C(F)(F)F)c3c2o1
Structure:
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