Reaction Details Report a problem with these data
Target
Vascular endothelial growth factor A
Ligand
BDBM107702
Substrate
n/a
Meas. Tech.
ELISA Assay
EC50
4.3e+3±n/a nM
Citation
 Kawamoto, RM; Wu, S; Warshakoon, NC; Evdokimov, AG; Greis, KD; Boyer, AS Prolyl hydroxylase inhibitors and methods of use US Patent  US8598210 Publication Date 12/3/2013 
Target
Name:
Vascular endothelial growth factor A
Synonyms:
VEGF | VEGF-A | VEGFA | VEGFA_HUMAN | VPF | Vascular endothelial growth factor (VEGF) | Vascular endothelial growth factor A (VEGF) | Vascular endothelial growth factor A (VEGF2) | Vascular permeability factor
Type:
Protein
Mol. Mass.:
27063.81
Organism:
Homo sapiens (Human)
Description:
P15692
Residue:
395
Sequence:
MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLGCSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
  
Inhibitor
Name:
BDBM107702
Synonyms:
US8598210, Table XV, 8 | US8722895, 8: {[5-(4-Cyanophenyl)-3-hydroxypyridine-2- carbonyl]amino}-acetic acid
Type:
Small organic molecule
Emp. Form.:
C15H11N3O4
Mol. Mass.:
297.2655
SMILES:
OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc(cc1)[N+]#[C-]
Structure:
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