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Target
Nuclear hormone receptor family member daf-12
Ligand
BDBM62936
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12)
EC50
67485±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12) PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear hormone receptor family member daf-12
Synonyms:
DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
84211.49
Organism:
Caenorhabditis elegans
Description:
gi_71987181
Residue:
753
Sequence:
MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQMSTPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRVCGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFTVGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYPPQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLTMMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLMNEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIPGNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAMIPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQMQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGVTRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAVYLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALGLLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK
  
Inhibitor
Name:
BDBM62936
Synonyms:
4,6-dimethyl-2-(5-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-ylamine | 4,6-dimethyl-2-(6-methyl-1H-benzimidazol-2-yl)-3-thieno[2,3-b]pyridinamine | 4,6-dimethyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-amine | MLS000547126 | SMR000115128 | [4,6-dimethyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-yl]amine | cid_845804
Type:
Small organic molecule
Emp. Form.:
C17H16N4S
Mol. Mass.:
308.401
SMILES:
Cc1ccc2nc([nH]c2c1)-c1sc2nc(C)cc(C)c2c1N
Structure:
Search PDB for entries with ligand similarity: