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Target
Nuclear hormone receptor family member daf-12
Ligand
BDBM49392
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12)
EC50
67527±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12) PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear hormone receptor family member daf-12
Synonyms:
DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
84211.49
Organism:
Caenorhabditis elegans
Description:
gi_71987181
Residue:
753
Sequence:
MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQMSTPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRVCGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFTVGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYPPQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLTMMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLMNEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIPGNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAMIPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQMQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGVTRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAVYLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALGLLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK
  
Inhibitor
Name:
BDBM49392
Synonyms:
6-methyl-2-(5-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-ylamine | 6-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-3-thieno[2,3-b]pyridinamine | 6-methyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-amine | MLS000547128 | SMR000115129 | [6-methyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-yl]amine | cid_845805
Type:
Small organic molecule
Emp. Form.:
C16H14N4S
Mol. Mass.:
294.374
SMILES:
Cc1ccc2nc([nH]c2c1)-c1sc2nc(C)ccc2c1N
Structure:
Search PDB for entries with ligand similarity: