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Target
Cyclin-dependent kinase 3
Ligand
BDBM124970
Substrate
n/a
Meas. Tech.
Kinase Screen Assay
Kd
250±n/a nM
Citation
 Choi, HG; Sim, T; Gray, N; Zhou, W; Chang, JW; Zhang, J; Weisberg, E Fused 2-aminothiazole compounds US Patent  US8765747 Publication Date 7/1/2014 
Target
Name:
Cyclin-dependent kinase 3
Synonyms:
CDK3 | CDK3/Cyclin E | CDK3_HUMAN | CDKN3 | Cyclin-dependent kinase 3 | Cyclin-dependent kinase 3 (CDK3)
Type:
Enzyme
Mol. Mass.:
35053.88
Organism:
Homo sapiens (Human)
Description:
Q00526
Residue:
305
Sequence:
MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVLQRFRH
  
Inhibitor
Name:
BDBM124970
Synonyms:
US8765747, 2
Type:
Small organic molecule
Emp. Form.:
C31H31F3N6O2S
Mol. Mass.:
608.677
SMILES:
CCN1CCN(Cc2ccc(NC(=O)c3cccc(c3)-c3ccc4nc(NC(=O)C5CC5)sc4n3)cc2C(F)(F)F)CC1
Structure:
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