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Target
Vascular endothelial growth factor A
Ligand
BDBM102350
Substrate
n/a
Meas. Tech.
ELISA Assay
IC50
7400±n/a nM
Citation
 Shalwitz, R; Gardner, JH Methods for increasing the stabilization of hypoxia inducible factor-1 alpha US Patent  US8778412 Publication Date 7/15/2014 
Target
Name:
Vascular endothelial growth factor A
Synonyms:
VEGF | VEGF-A | VEGFA | VEGFA_HUMAN | VPF | Vascular endothelial growth factor (VEGF) | Vascular endothelial growth factor A (VEGF) | Vascular endothelial growth factor A (VEGF2) | Vascular permeability factor
Type:
Protein
Mol. Mass.:
27063.81
Organism:
Homo sapiens (Human)
Description:
P15692
Residue:
395
Sequence:
MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLGCSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
  
Inhibitor
Name:
BDBM102350
Synonyms:
US10562854, No. F3 | US8536181, F3 | US9278930, F3
Type:
Small organic molecule
Emp. Form.:
C12H10ClNO2
Mol. Mass.:
235.666
SMILES:
Oc1cccn(Cc2ccc(Cl)cc2)c1=O
Structure:
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