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Target
Regulator of G-protein signaling 8
Ligand
BDBM50384774
Substrate
n/a
Meas. Tech.
Inhibitory Assay
IC50
11000±n/a nM
Citation
 Neubig, R; Blazer, L; Husbands, S; Larsen, S; Traynor, J Small molecule inhibitors of RGS proteins US Patent  US8865750 Publication Date 10/21/2014 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM50384774
Synonyms:
CHEMBL1917204 | US20230414581, Compound 6
Type:
Small organic molecule
Emp. Form.:
C16H13FN2O2S
Mol. Mass.:
316.35
SMILES:
Cc1ccc(cc1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O
Structure:
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