Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 8
Ligand
BDBM136369
Substrate
n/a
Meas. Tech.
Inhibitory Assay
IC50
>100000±n/a nM
Citation
 Neubig, R; Blazer, L; Husbands, S; Larsen, S; Traynor, J Small molecule inhibitors of RGS proteins US Patent  US8865750 Publication Date 10/21/2014 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM136369
Synonyms:
US8865750, CCG- 203780
Type:
Small organic molecule
Emp. Form.:
C11H8BrNO2
Mol. Mass.:
266.091
SMILES:
BrC1=CC(=O)N(Cc2ccccc2)C1=O |t:1|
Structure:
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