Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM286143
Substrate
n/a
Meas. Tech.
AlphaScreen SureFire Assay
Temperature
298.15±n/a K
EC50
1550±n/a nM
Comments
extracted
Citation
 Shi, Y; Cheng, PT; Wang, Y; Wu, SC; Zhang, H Bicyclo [2.2.1] acid GPR120 modulators US Patent  US9518000 Publication Date 12/13/2016 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM286143
Synonyms:
4-(4-(2- isopropoxy- benzyloxy)bicyclo [2.2.1]heptan- 1-yl)butanoic acid | US9518000, Example 36
Type:
Small organic molecule
Emp. Form.:
C21H30O4
Mol. Mass.:
346.4605
SMILES:
CC(C)Oc1ccccc1COC12CCC(CCCC(O)=O)(CC1)C2
Structure:
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