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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM153463
Substrate
n/a
Meas. Tech.
Fluorescent-Based (Inhibitor) Screening Assay
pH
7.5±n/a
IC50
1500±n/a nM
Comments
extracted
Citation
 Guibourt, N; Ortega Munoz, A; Castro-Palomino Laria, J Phenylcyclopropylamine derivatives and their medical use US Patent  US8993808 Publication Date 3/31/2015 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM153463
Synonyms:
US8993808, 61
Type:
Small organic molecule
Emp. Form.:
C21H25NO
Mol. Mass.:
307.4293
SMILES:
CC1(C)CCc2cc(CN[C@H]3CC3c3ccccc3)ccc2O1 |r|
Structure:
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