Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM158253
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Temperature
310.15±n/a K
Ki
1.2±n/a nM
Comments
extracted
Citation
 Galley, G; Norcross, R; Pflieger, P Substituted benzamide derivatives US Patent  US9029370 Publication Date 5/12/2015 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM158253
Synonyms:
US9029370, 47
Type:
Small organic molecule
Emp. Form.:
C19H17ClF2N4O3
Mol. Mass.:
422.813
SMILES:
FC(F)Oc1ccc(cc1NC(=O)Nc1ccc(cc1Cl)[C@@H]1CNCCO1)C#N |r|
Structure:
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