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Target
Methyl-CpG-binding protein 2
Ligand
BDBM47368
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
2810±n/a nM
Citation
 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z Agents for reversing epigenetic silencing of genes US Patent  US9034574 Publication Date 5/19/2015 
Target
Name:
Methyl-CpG-binding protein 2
Synonyms:
MECP2 | MECP2_HUMAN | Small conductance calcium-activated potassium channel protein 3
Type:
n/a
Mol. Mass.:
52482.84
Organism:
Homo sapiens (Human)
Description:
P51608
Residue:
486
Sequence:
MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS
  
Inhibitor
Name:
BDBM47368
Synonyms:
BDBM77674 | US9034574, XXIV
Type:
n/a
Emp. Form.:
C17H15N3O2
Mol. Mass.:
293.3199
SMILES:
COc1ccc(NC(=O)Nc2cccc3cccnc23)cc1
Structure:
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