Reaction Details Report a problem with these data
Target
Tyrosinase
Ligand
BDBM175275
Substrate
n/a
Meas. Tech.
Tyrosinase Activity
pH
6.8±n/a
IC50
1.6621e+5±n/a nM
Comments
extracted
Citation
 Ismail, T; Shafi, S; Srinivas, J; Sarkar, D; Qurishi, Y; Khazir, J; Alam, MS; Kumar, HM Synthesis and tyrosinase inhibition activity of trans-stilbene derivatives. Bioorg Chem 64:97-102 (2016) [PubMed]  Article 
Target
Name:
Tyrosinase
Synonyms:
TYRO_MOUSE | Tyr
Type:
Protein
Mol. Mass.:
60600.74
Organism:
Mus musculus (Mouse)
Description:
n/a
Residue:
533
Sequence:
MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILLSSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIRRNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMHYYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRDAENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRNPGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQSSMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGHNRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLGAALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
  
Inhibitor
Name:
BDBM175275
Synonyms:
Trans-9-Styryl-anthracene (15)
Type:
Small organic molecule
Emp. Form.:
C22H16
Mol. Mass.:
280.3624
SMILES:
C(=C\c1c2ccccc2cc2ccccc12)\c1ccccc1
Structure:
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