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Target
Trypsin
Ligand
BDBM191631
Substrate
n/a
Meas. Tech.
High-Throughput Screening Assay
IC50
31200±2000 nM
Citation
 Vasioukhin, VI; Chevillet, JR Hepsin inhibitors US Patent  US9182402 Publication Date 11/10/2015 
Target
Name:
Trypsin
Synonyms:
TRYP_PIG
Type:
PROTEIN
Mol. Mass.:
24411.24
Organism:
Sus scrofa
Description:
ChEMBL_1450738
Residue:
231
Sequence:
FPTDDDDKIVGGYTCAANSIPYQVSLNSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN
  
Inhibitor
Name:
BDBM191631
Synonyms:
US9182402, 5
Type:
Small organic molecule
Emp. Form.:
C19H15F3N2O2
Mol. Mass.:
360.3298
SMILES:
[O-][N+](=O)c1ccc(cc1)C1Nc2c(cccc2C(F)(F)F)C2C=CCC12 |c:24|
Structure:
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