Reaction Details Report a problem with these data
Target
Cathepsin B
Ligand
BDBM192658
Substrate
n/a
Meas. Tech.
Proteolytic Activity Assay
pH
5±0
Temperature
310.15±0 K
Ki
113±0.0 nM
Citation
 Garg, S; Raghav, N 2,5-Diaryloxadiazoles and their precursors as novel inhibitors of cathepsins B, H and L. Bioorg Chem 67:64-74 (2016) [PubMed]  Article 
Target
Name:
Cathepsin B
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
36777.57
Organism:
Capra hircus (Goat)
Description:
n/a
Residue:
335
Sequence:
MWQLLATLSCLLVLTSARSSLHFPPLSDEMVNYVNKQNTTWKAGHNFYNVDLSYVKKLCGAILGGPKLPQRDAFAADMVLPDSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSKGRVNVEVSAEDMLTCCGSECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPSYKDDKHFGCSSYSVSSNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEMMGGHAIRILGWGVENDTPYWLVGNSWNTDWGDKGFFKILRGQDHCGIESEIVAGMPCTHQY
  
Inhibitor
Name:
BDBM192658
Synonyms:
N’-(2-nitrophenylmethylene)benzohydrazide (1i)
Type:
Small organic molecule
Emp. Form.:
C14H11N3O3
Mol. Mass.:
269.2554
SMILES:
[O-][N+](=O)c1ccccc1\C=N\NC(=O)c1ccccc1
Structure:
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