Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM633466
Substrate
n/a
Meas. Tech.
Human Adenosine A1 Receptor Binding Assay
Ki
<100±n/a nM
Citation
 Kim, K; Kim, J; Moon, A; Song, D; Lee, Y; Jung, J Prevention and/or treatment of CNS disorders US Patent  US11806350 Publication Date 11/7/2023 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM633466
Synonyms:
US11806350, Compound 206
Type:
Small organic molecule
Emp. Form.:
C20H16FN7
Mol. Mass.:
373.3863
SMILES:
Cc1cc(Cn2ncc3c(nc(N)nc23)-c2cccc(C#N)c2F)ccc1N
Structure:
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