Reaction Details Report a problem with these data
Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM232950
Substrate
n/a
Meas. Tech.
Transactivation Assay
Temperature
310.15±n/a K
EC50
8000±0.0 nM
Comments
extracted
Citation
 Bouix-Peter, C Oxazetidine derivatives, process for preparing them and use in human medicine and in cosmetics US Patent  US9353083 Publication Date 5/31/2016 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Homo sapiens (Human)
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM232950
Synonyms:
US9353083, 1
Type:
Small organic molecule
Emp. Form.:
C30H38N4O5
Mol. Mass.:
534.6465
SMILES:
COc1ccc(C[C@@H](NC(=O)CCc2c[nH]cn2)C(=O)N2CC(C2)(OCCCCO)c2ccccc2C)cc1
Structure:
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