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Target
Proto-oncogene tyrosine-protein kinase Src [251-533]
Ligand
BDBM234861
Substrate
n/a
Meas. Tech.
In vitro Kinase Assay
pH
8±n/a
IC50
2170±n/a nM
Comments
extracted
Citation
 Garske, AL; Shokat, KM Methods and compositions for kinase inhibition US Patent  US9353116 Publication Date 5/31/2016 
Target
Name:
Proto-oncogene tyrosine-protein kinase Src [251-533]
Synonyms:
Proto-oncogene tyrosine-protein kinase Src | Proto-oncogene tyrosine-protein kinase Src (c-Src) | SRC | SRC_CHICK
Type:
Protein
Mol. Mass.:
32360.42
Organism:
Gallus gallus (Chicken)
Description:
Wild-type chicken c-Src kinase domain (251-533aa)
Residue:
283
Sequence:
QTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
  
Inhibitor
Name:
BDBM234861
Synonyms:
US9353116, 20
Type:
Small organic molecule
Emp. Form.:
C18H18N4O4S
Mol. Mass.:
386.425
SMILES:
COc1cc2ncnc(Nc3ccc(NS(=O)(=O)C=C)cc3)c2cc1OC
Structure:
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