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Target
Proto-oncogene tyrosine-protein kinase Src [251-533,V323A,T338C]
Ligand
BDBM234844
Substrate
n/a
Meas. Tech.
In vitro Kinase Assay
pH
8±n/a
IC50
67±n/a nM
Comments
extracted
Citation
 Garske, AL; Shokat, KM Methods and compositions for kinase inhibition US Patent  US9353116 Publication Date 5/31/2016 
Target
Name:
Proto-oncogene tyrosine-protein kinase Src [251-533,V323A,T338C]
Synonyms:
Proto-oncogene tyrosine-protein kinase Src (T338C/V323A) | SRC | SRC_CHICK
Type:
Protein
Mol. Mass.:
32334.41
Organism:
Gallus gallus (Chicken)
Description:
residues 251-533
Residue:
283
Sequence:
QTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLAQLYAVVSEEPIYIVCEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
  
Inhibitor
Name:
BDBM234844
Synonyms:
US9353116, 13
Type:
Small organic molecule
Emp. Form.:
C17H18FN5O
Mol. Mass.:
327.3561
SMILES:
CC(C)n1nc(Cc2cccc(c2)C(=O)CF)c2c(N)ncnc12
Structure:
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