Reaction Details Report a problem with these data
Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM240746
Substrate
n/a
Meas. Tech.
Cell Based Assay
pH
7.4±n/a
Temperature
310.15±n/a K
EC50
63±n/a nM
Comments
extracted
Citation
 Martos, JL; Carling, WR; Woodward, DF; Wang, JW; Kangasmetsa, JJ Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response US Patent  US9422273 Publication Date 8/23/2016 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Homo sapiens (Human)
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM240746
Synonyms:
US9422273, 12d
Type:
Small organic molecule
Emp. Form.:
C30H39F3N4O7S
Mol. Mass.:
656.713
SMILES:
FC(F)(F)S(=O)(=O)NC(=O)CCc1cc2OCOc2cc1CN1CCC[C@H]1c1nc(co1)C(=O)NCCCCC1CCCCC1 |r|
Structure:
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