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Target
Serine protease 1
Ligand
BDBM240790
Substrate
n/a
Meas. Tech.
Tyrpsin Amidolytic Assay
pH
7.5±n/a
Ki
26300±1900 nM
Comments
extracted
Citation
 Markowska, A; Bruzgo, M; Surazynski, A; Midura-Nowaczek, K Tripeptides with non-code amino acids as potential serine proteases inhibitors. J Enzyme Inhib Med Chem 28:639-43 (2013) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM240790
Synonyms:
H-D-Ser-Phg-Arg-OH (1)
Type:
Small organic molecule
Emp. Form.:
C18H28N6O5
Mol. Mass.:
408.4521
SMILES:
N[C@@H](CO)C(=O)N[C@@H](CC(=O)N[C@H](CCCNC(N)=N)C(O)=O)c1ccccc1 |r|
Structure:
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