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Target
Cannabinoid receptor 2
Ligand
BDBM249243
Substrate
n/a
Meas. Tech.
PathHunter Beta-Arrestin Assay
EC50
5.4±0.0 nM
Citation
 Blackburn, AC; Han, S; Jones, RM; Montalban, AG; Pal, BB; Rueter, JK Crystalline forms and processes for the preparation of cannabinoid receptor modulators US Patent  US9458136 Publication Date 10/4/2016 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM249243
Synonyms:
US9458136, 1
Type:
Small organic molecule
Emp. Form.:
C18H23N5O3
Mol. Mass.:
357.4069
SMILES:
CC(C)(C)C(CO)NC(=O)c1nn(c2[C@H]3C[C@H]3Cc12)-c1c[n+]([O-])ccn1 |r|
Structure:
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