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Target
Leukotriene B4 receptor 1
Ligand
BDBM406377
Substrate
n/a
Meas. Tech.
BLT-1 cAMP Assay
EC50
2037±n/a nM
Citation
 Han, Y; Lim, J; Tummanapalli, S; Siliphaivanh, P; Spencer, K Aryl acylsulfonamides as BLT1 antagonists US Patent  US10336733 Publication Date 7/2/2019 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM406377
Synonyms:
2-((3R,4S or 3S,4R)-3-Benzyl-4-hydroxychroman-7-yl)-N-((1-methylcyclopropyl)sulfonyl)benzamide | US10336733, Example 21
Type:
Small organic molecule
Emp. Form.:
C27H27NO5S
Mol. Mass.:
477.572
SMILES:
CC1(CC1)S(=O)(=O)NC(=O)c1ccccc1-c1ccc2[C@@H](O)[C@H](Cc3ccccc3)COc2c1 |r|
Structure:
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