Reaction Details Report a problem with these data
Target
Interleukin-2
Ligand
BDBM412448
Substrate
n/a
Meas. Tech.
Human ELISA assay
IC50
78.0±n/a nM
Citation
 Chen, S; Bohnert, G; Jiang, J; Xia, Z Compounds for inflammation and immune-related uses US Patent  US10399967 Publication Date 9/3/2019 
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Homo sapiens (Human)
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM412448
Synonyms:
US10399967, Compound 78 | methyl 4-(1-(5-(5-fluoro-4- methylnicotinamido)pyrazin-2- yl)cyclopropyl)benzoate
Type:
Small organic molecule
Emp. Form.:
C22H19FN4O3
Mol. Mass.:
406.4097
SMILES:
COC(=O)c1ccc(cc1)C1(CC1)c1cnc(NC(=O)c2cncc(F)c2C)cn1
Structure:
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